{
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  "_kind": "LibrarySkill",
  "_file": "generated-library/skills.yaml",
  "_cluster": "generated-library",
  "attributes": {
    "displayName": "tmb-msi-calculator",
    "description": "Tumor mutation burden and microsatellite instability calculation skill for immunotherapy biomarkers",
    "libraryPath": "library/specializations/domains/science/bioinformatics/skills/tmb-msi-calculator/SKILL.md",
    "specialization": "bioinformatics",
    "contentSummary": "# TMB-MSI Calculator Skill\n\n## Purpose\nCalculate tumor mutation burden and microsatellite instability for immunotherapy biomarker assessment.\n\n## Capabilities\n- TMB calculation from VCF\n- MSI status determination\n- Neoantigen prediction\n- HLA typing integration\n- Biomarker thresholds\n- Clinical repo"
  },
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